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2022;42:BSR20212808
Research protocols typically employ intermittent dosing strategies (once weekly or 3-day cycles) designed to prevent excessive apoptosis while enabling effective senescent cell elimination, with doses ranging from 5-10 mg/kg body weight in animal studies
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In cases where hypersensitivity is confirmed, desensitization protocols have been developed to allow patients to continue receiving necessary vitamin B12 supplementation safely
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doi: 10.4103/2229-5178.110593
