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Skin gets what's left over
Extracellular turnover of free coenzyme A can proceed via dephosphorylation to 3-dephospho-CoA or via hydrolysis yielding 3-phosphoadenosine 5-phosphate (PAP) and 4-phosphopantetheine
doi: 10.1016/j.celrep.2019.06.018 42 JhaAKHuangSC-CSergushichevALampropoulouVIvanovaYLoginichevaEet al

Environ Health: A Global Access Sci Source 19(1):25

However, their effects on bone integrity remain complex, with some evidence indicating bone-protective mechanisms while others suggest potential increases in bone resorption associated with weight loss

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