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The compound regulates miRNA expression through AMPK signaling pathway activation and chromatin remodeling, with PDCD4 protein levels increasing by 60% following miR-21 inhibition (101)
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doi: 10.3945/ajcn.2009.28095 63 CaniPDPossemiersSVan de WieleTGuiotYEverardARottierOet al

Update on the serrated pathway to colorectal carcinoma
