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In another study, a mouse model of Huntingtons disease (HD) underwent 12 weeks of treadmill exercise, 3 times a day

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This may cause vascular leakage, widened endomysium, and fragmentation of muscle fibers that may be related to edema and accumulation of mucopolysaccharides resulting from necrotic changes ( The previous findings were supported by Massons trichrome-stained sections, which showed a highly significant increase in the area percentage of collagen fibers

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