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Based on the above, we believe that it would be useful to identify individuals with IR both before they develop HF and during the course of HF in order to attempt to prevent or, at least, slow down the negative progression of HF, including through interventions designed to counteract IR

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Glutathione peroxidase 4 (GPX4), a member of the GPX family, has three isoforms: nuclear, cytosolic, and mitochondrial

AsA-GSH cycle forms the main H 2 O 2 -detoxification system operating in cytosol, chloroplasts and mitochondria of plant cells (Noctor and Foyer, 1998

It is stable and resistant to hydrolysis or digestion by enzymes

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