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Some protocols recommend a five-day-on, two-day-off schedule

Kamierczak-Baraska J, Boguszewska K, Adamus-Grabicka A, Karwowski BT (2020) Two faces of vitamin C-antioxidative and pro-oxidative agent

Diammonium glycyrrhizinate supplementation in mice lowers BSH-enriched bacteria, increasing taurine-conjugated BAs, inhibiting ileal FXR-FGF15 feedback signaling, suppressing CYP7A1 expression, altering the BA profile, and improving metabolism, including lowering blood glucose and insulin levels, enhancing insulin sensitivity, reducing hepatic steatosis, and resisting weight gain [83]

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