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Gislason, G
the pathogen-induced ROS production includes direct production by pathogens where many pathogens, such as bacteria and viruses, may generate ROS directly during their metabolic activities, consequently this causes activation of the host's immunological response, specifically neutrophils, and macrophages

HDL are anti-infectious, anti-parasitic, and anti-viral

This pathway signals through Gq-phospholipase C-IP3 cascades, increasing intracellular calcium and promoting GH vesicle exocytosis

Urate, also known as uric acid, is a major endogenous antioxidant that is neuroprotective against both astrocyte-induced toxicity in SOD1 G93A mice and H 2 O 2 induced oxidative stress in cells expressing mutant SOD1 G93A (Bakshi et al., G85R cellular and Drosophila models (Zhang et al., 2019b)
