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In conclusion, combinatorial treatment with BSO and auranofin could serve as a potential therapeutic strategy in pancreatic ductal adenocarcinoma.

The glutathione-responsive, chemotherapeutic and photothermal synergistic drug delivery systems (DDS) were developed using degradable dendritic mesoporous silica nanoparticles (DDMSNs) as carriers, camptothecin (CPT) as antitumor drug, and bovine serum albumin (BSA)/CuS as photothermal reagents (denoted as DDMSNs-CPT-CuS)

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GPX2 inversely correlated with expression of multiple pro- inflammatory cytokines/chemokines and NF-kB activation in cell lines and knockdown of GPX2 led to increased secretion of prostaglandin E2 (PGE2) and interleukin-6

8. Panthenol (Pro-Vitamin B5)