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Description
Patients with Grade III gliomas lacking 1p/19q codeletion and harboring IDH mutations have significantly prolonged progression-free survival (PFS) and overall survival (OS), with similar trends observed in secondary high-grade gliomas (HGGs)

Oxidative stress can trigger zinc release from the binding sites, leading to conformational changes of these proteins

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Stat Appl Genet Mol Biol 3 : Article3

doi: 10.1007/s10194-009-0142-2

If you treat the root cause, the symptoms should go away in turn
