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Practical safety guidance: If you have established cardiovascular disease, chronic kidney disease, or a history of vascular events, discuss L-carnitine with your clinician before starting

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There were early studies suggesting a potential association with the HCV-3 genotype and greater severity of fibrosis, but these retrospective studies were limited by small cohorts, variability in patient characteristics such as insulin resistance or Body Mass Index (BMI) or HCV genotype distribution, and inconsistencies in methodology, particularly with respect to the grading of steatosis[13,14]

Truth vs Myths About L-Carnitine Myth 1: L-Carnitine damages kidneys There is no strong clinical evidence showing kidney damage in healthy individuals using recommended doses