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Description
The concentrations in other tissues were lower than the average concentration in the plasma and are presented in the descending order as follows: intestinal tract, lung, gonad, skin, skeletal muscle, cardiac muscle, whole blood, brain, and body fat

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[DOI] [PMC free article] [PubMed] [Google Scholar] 185.Chang C.H., Tsai W.C., Hsu Y.H., Pang J.H

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The key difference is concentration
In this condition, inflammation usually starts in the rectum and can extend throughout the colon