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Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion

Indoxyl sulfate, a uremic toxin, stimulates reactive oxygen species production and erythrocyte cell death supposedly by an organic anion transporter 2 (OAT2) and NADPH oxidase activity-dependent pathways

Stirban A, Negrean M, Stratmann B, Gawlowski T, Horstmann T, Gotting C, et al

Recent research highlights that inhibition of its rate-limiting enzyme, AR, may substantially mitigate vascular dysfunction and related complications in DM [19, 147]

Plants 14, 2995

(3) It plays a crucial role in counteracting NF-B-inducing inflammatory response
