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Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human lLeukemia cells

The administration into the blood of Hu5F9-G4 revealed that it can pass through the blood-brain endothelial barrier (BBB) apparently even when the tumor was not present

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In this established model, to study the clustering of AChRs, myotubes are exposed to the compound/sample of interest (such as recombinant agrin, patients plasmas, or purified antibody preparations) up to 16 h to allow full cluster maturation