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In one aspect, the invention provides methods of preventing or treating muscular weakness in a patient with Parkinson's disease and/or of improving or restoring muscular strength of a patient with Parkinson's disease, by administering one or more hepatocyte growth factor mimics as described herein

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Reduced Joint Deterioration: Histological analysis in animal studies showed that AOD-9604-treated joints had lower degeneration scores compared to untreated controls