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The outcome of the mentioned mechanism is prolonged muscle contraction, which leads to muscle cramps

[DOI] [Google Scholar] 184.Handelsman Y, Henry RR, Bloomgarden ZT, et al

Thus, de-energization of resting cells and, probably, also cofactor leak or degradation, are a major drawback for continuous use in biotransformation

doi: 10.3389/fmicb.2023.1196239 11

Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-B and p38MAPK/CREB signaling pathways
