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The obese hypertensive rats also presented with a significantly reduced testosterone: estradiol ratio (130)
[PubMed] [Google Scholar] Tlak Gajger I, Ribari J, Smodi kerl M, Vlaini J, Sikiri P

These effects were confirmed in hemopexin knock-out mouse models, nominating c-MYC as a heme-regulated gene [48]

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Phytomedicine 8 , 252261 (2001)

Zgorzynska et al
