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I.BurghardtL

Innate and adaptive immunity in inflammatory bowel disease

The synthesis of GSH depends on the availability of cysteine, maintained primarily by System Xc-, a cystine/glutamate antiporter composed of SLC7A11 (xCT) and SLC3A2 (CD98)

D.KlaassenC

Notably, enforced expression of KEAP1 in Cis_NR T24 and J82 cells sensitized them to cisplatin in a dose-dependent manner, further confirming the critical role of KEAP1 in mediating chemosensitivity (Supplementary Fig

doi: 10.1016/j.redox.2022.102441
