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The Jumonji family: past, present and future of histone demethylases in cancer

The primary objective of this study was to assess the safety and tolerability of a single intravenous infusion of pegadricase (also known as SEL-037) in an ascending cohort dose escalation study

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237 However, the histone marker alteration patterns differ in different stress-induced premature senescence cells based on various stress factors
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