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It signals fibroblasts to build collagen and elastin, activates angiogenesis (new capillary growth), reduces inflammatory cytokines like TNF-alpha, and helps stem cells migrate to repair sites

The two most notorious culprits are Proton Pump Inhibitors (PPIs) , used for acid reflux, and Metformin , the first-line treatment for Type 2 diabetes

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He had no other haematological abnormalities at initial presentation or at his current relapse
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