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These alterations manifest across diverse adipose-resident cell populations - mature adipocytes, immune cell subsets, and progenitor compartments (405) - culminating in systemic inflammatory activation, insulin resistance development, and accelerated aging phenotypes (406)
Oncogenes and pro-oncogenic genes are poorly studied in CR and carcinogenesis contexts Searching in PubMed revealed only 32.2% (39/121) of our CR cancer-associated genes (Supplementary Data 7) are associated with terms caloric or calorie or caloric restriction or calorie restriction or dietary restriction
[cited 2023 June 22] 5
This preservation of peptide integrity can lead to enhanced efficacy and consistency in achieving accurate outcomes in peptide research
