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Moreover, ROS can also react with nitric oxide to form reactive nitrogen species (RNS) like peroxynitrite, which further contribute to oxidative stress and disrupt nitric oxide-mediated signaling (Brown and Borutaite 2006)

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RAB-10 Promotes EHBP-1 bridging of filamentous actin and tubular recycling endosomes

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In the setting of microbial infection, PAMPs derived from the invading microbes are recognized by pattern recognition receptors (PRRs) present in the cytosol or at the cell surface of macrophages and other innate immune cells

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