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This class was first studied and proposed based on its prototypical member, the neurite outgrowth inhibitor (Nogo-A)

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Edgren G., Hjalgrim H., Rostgaard K., et al., Transmission of Neurodegenerative Disorders through Blood Transfusion: A Cohort Study, Annals of Internal Medicine 165, no

Studies found that Mdivi-1 rescued evoked dopamine release in PINK1 knockout mice and improved evoked dopamine release in mice pre-lesioned with MPTP (122)

It has been documented that selenium-enriched yeast can reduce metastasis in a murine model of Lewis lung carcinoma (70)

GLYI and D-LDH thus are key players in MG detoxification