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An excess of estrogens, deficit of progesterone, or dominance of estrogens can cause increased production of PGE-2, resulting in migraine

The interplay between macrophages and angiogenesis in development, tissue injury and regeneration

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Genome-wide studies have shown that circadian sampling in rodents, non-human primates, and human tissues indicates that over 80% of FDA-approved drug targets exhibit daily rhythms (Zhang et al., 2014

doi: 10.1093/alcalc/agq040 48
