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In the context of periodontitis, the increased expression of SLC7A11 likely represents a compensatory response to elevated oxidative stress, as ferroptosis characterized by iron-dependent lipid peroxidation has been shown to be involved in inflammatory diseases including periodontitis [24]

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doi: 10.1016/j.ajpath.2014.10.009 134 Veses-GarciaM.LiuX.RigdenD

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In a study over 70 patients, Repp et al