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[DOI] [PubMed] [Google Scholar] 37.Ilic S, Drmic D, Zarkovic K, Kolenc D, Coric M, Brcic L, et al

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Mitochondrial dysfunction in POI is characterized by a reduction in mitochondrial DNA (mtDNA) copy number, increased oxidative damage, and pathogenic mutations that compromise the oxidative phosphorylation (OXPHOS) system [105]

This result signifies that Dihexas protection is likely by mediating the response of an aminoglycoside-specific target that is not shared by cisplatin
