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[DOI] [PMC free article] [PubMed] [Google Scholar] 246.Hiraga T, Hata T, Soya S, Shimoda R, Takahashi K, Soya M, et al

To measure the effect of the paramagnetic label, 1 H, 15 N and 1 H, 13 C HSQC spectra with long inter-scan delays (3 s) of 100 M 13 C/ 15 N-labeled p53 TAD2 in presence of one stoichiometric equivalent paramagnetically labeled FOXO4 FH were recorded before and after addition of 5 mM ascorbic acid

This is an important early study on experimental rotational head injury in monkeys that demonstrates a direct relationship between the amount of rotational head motion and the severity of DAI, and in turn the duration of coma and the degree of neurological impairment

These elements support the relation between this condition and systemic inflammation, due to the ethanol-mediated activation of nuclear factor-B (NF-B) signaling pathway, which could alter gut barrier integrity, increasing portal and systemic endotoxemia

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