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First, LCS3 treatment induced GSH inhibition in VRK2-KO cells, reflected by decreased levels of GSH/GSSG, whereas no significant effect on TXNRD1 activity was verified by the same concentration of LCS3

10.1111/bcp.16249 82 TakeyamaK.AgustC.UekiI.LausierJ.CardellL

3-aminobenzamide (3-AB) is a competitive inhibitor of PARP enzymes, particularly PARP1 171,172