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Thus, RpiB is a potential therapeutic target for treating diseases such as African Sleeping Sickness, Chagas disease, and leishmaniasis

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In addition, periodontal treatment and psychological treatment should not be neglected

A recent study suggested that combinations of metallopolymers with ineffective antibiotics exhibit synergy against MDR pathogens like E

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The 4.3 kb adenoviral fragment contains early region 1 (E1) transcription units E1A and E1B, integrated into chromosome 19 of the host genome 61,62 , enabling viral gene expression and therapeutic protein overexpression under viral, mammalian, or synthetic promoters