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By establishing kinds of liver fibrosis models-TAA-induced zebrafish model, CCL 4 -induced mice model, and activated HSC-T6 cells and JS-1 cells, we provided compelling evidence of the anti-fibrotic effects of Ag

50 L of supernatant was mixed with 450 L of 40 mM Tris-HCl buffer and 10 L of 10 M 2,7-dichlorofluorescein diacetate and incubated at 37C for 30 min in the dark

doi: 10.2174/1567205014666170505094549

Acknowledgements This work was supported by the Japan Society for the Promotion of Science, grant numbers 20K07623 and 16K08722

In addition, low glutathione levels are linked to impaired mitochondrial function and reduced fatty acid oxidation , both of which contribute to insulin resistance (4)

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