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In PRCA, CEBPB recruits DNA methyltransferases to epigenetically silence ER, facilitating proliferation and apoptosis resistance [77] CEBPB, as a key epigenetic regulator in ovarian cancer chemoresistance, recruits DOT1L to mediate H3K79 methylation, maintain open chromatin at drug-resistance genes [112]

Microbial metabolites influence lipid composition of membranes and fat stores 3,4,5 , modulate signaling pathways that regulate host immune function 6,7 , and provide diet-derived metabolic feedback 8,9

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Luminal Small Intestinal Digestion of Cholesteryl Esters Digestion of cholesteryl esters also occurs in the small intestinal lumen

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus