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Accordingly, a large number of factors, including metabolites [79], stressors [80], and several biological agents, such as bacteria, viruses, and fungi, have been reported to cause reactivation [81]

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Glutathione synthesis can be impaired by cysteine depletion, protein-energy malnutrition, hyperglycemia, glucocorticoid at pharmacologic doses, and decreased secretion of anterior pituitary hormones (growth hormones, thyrotropin, gonadotropins), as often observed in prolonged critical illness

doi: 10.3748/wjg.v20.i31.10825 534 BaoBAliSBanerjeeSWangZLognaFAzmiASet al

Peptides are short chains of amino acidsbasically tiny building blocks of proteins