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Notch signaling is also considered a key player in carcinogenesis, acting as either an oncogene or a tumor suppressor in various malignancies, including different TC histotypes, thus suggesting that its apparent dual role is cell type and context-dependent [152,153]

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During the inflammatory phase, inflammatory cells infiltrate the injury site, followed by fibroblast proliferation and the synthesis of collagen fibers in the repair phase

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Agrobacterium -mediated transformation and confirmation of transgenic plants We followed an efficient protocol of tomato transformation and selection of transgenic plants 53 with some modifications