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GH exerts autocrine/paracrine effects by binding to GHR in the same or a neighboring cell surface and initiating JAK2- and SRC-mediated signaling cascades, which decrease pro-apoptotic molecules (Bax and PPAR) and suppress caspase protein activation (Figure 4A)

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[PubMed] [Google Scholar] 38.Sakamoto Y, Ishikawa T, Kondo Y, Yamaguchi K, Fujisawa M

Instead of a balanced progression, hair follicles prematurely shift into the telogen phase, resulting in excessive shedding, also known as telogen effluvium

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