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Complete rest from aggravating activities for at least the first 2 to 4 weeks of treatment allows the enhanced healing response to gain traction before gradually reintroducing load

TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation

Chest 147 , 10861093 (2015)

Certain medicines are also associated with reduced B12 absorption, most notably metformin (used in type 2 diabetes) and long-term use of proton pump inhibitors (PPIs) or H2-receptor antagonists

Abumrad NA, El-Maghrabi MR, Amri E-Z, Lopez E, Grimaldi PA

[DOI] [PubMed] [Google Scholar] 5.Teng M.L., Ng C.H., Huang D.Q., Chan K.E., Tan D.J., Lim W.H., Yang J.D., Tan E., Muthiah M.D