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Although melatonin does not target directly bipolar symptoms, improvement in sleep is an important factor in preventing mood disturbances in patients with bipolar disorder

[PubMed] [Google Scholar] 59.Terlecky S.R., Koepke J.I., Walton P.A

Ultimately, the application of isotope tracers was transformative, moving beyond correlative expression analyses to provide causal, quantitative evidence that the SETSHMT2 axis functionally drives one-carbon metabolism

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2-OHE 2 can bind to estrogen receptors but with markedly lower affinity

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