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Protandim treatment also increased microvessel density in the cremaster muscle of HS-fed Sprague-Dawley rats, a valuable experimental model of microvascular rarefaction [16,19,40]

Pyruvate kinase (PK) is the final rate-limiting enzyme in glycolysis and catalyzes the conversion of phosphoenolpyruvate to pyruvate 28

It has been demonstrated that the levels of lipid peroxidation products positively correlate with the FM severity evaluated by the Fibromyalgia Impact Questionnaire-Revised (FIQR) [25, 26]

No individual-level data were involved, and no additional informed consent is needed in this study

Physiol Plant 129:747755 Cohu CM, Abdel-Ghany SE, Gogolin Reynolds KA, Onofrio AM, Bodecker JR, Kimbrel JA, Niyogi KK, Pilon M (2009) Copper delivery by the copper chaperone for chloroplast and cytosolic copper/zinc-superoxide dismutases: regulation and unexpected phenotypes in an Arabidopsis mutant
