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SULFATION SAFE PATHWAY (SULT enzymes) 30-35% of acetaminophen in healthy non-pregnant adults Attaches sulfate groups for safe elimination Non-toxic pathway DECREASES 33% during pregnancy (contrary to previous assumptions)[] Limited capacityeasily saturated with repeated doses Predominant pathway in fetuses/children (60-70%) but quickly overwhelmed 3

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[DOI] [PubMed] [Google Scholar] 69.McClain CJ, Twyman DL, Ott LG, Rapp RP, Tibbs PA, Norton JA, et al

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Bodnar LM, Tang G, Ness RB, Harger G, Roberts JM: Periconceptional multivitamin use reduces the risk of preeclampsia
