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In addition, impaired mitochondrial function and intracerebral lactic acidosis caused by reduced COX activity in the brain may also contribute to the degeneration of neurons in these patients

Metabolomics 9, Suppl

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In contrast, long-term cagrilintide treatment in rats upregulates prolactin-releasing hormone ( Prlh ) expression in nucleus of the solitary tract Calcr/Prlh cells that are conserved across rodents, macaques and humans

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doi: 10.3390/ijms21030836 81 GearingAJBeckettPChristodoulouMChurchillMClementsJDavidsonAHet al
