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Phase II human trials of thymosin beta-4 (TB-500's parent molecule) have been conducted examining tissue repair rates, with studies reporting acceleration of repair in patients with pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds, though detailed results remain limited in peer-reviewed literature

(3) P.Sikiric et al (2016) Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications Current Neuropharmacology, 2016 Nov

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Conversely, the damaged mitochondrial function can induce aberrant A production and promote abnormal phosphorylation of tau [50]