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10.1371/journal.pone.0018250 26 IzzoN

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Despite the inconsistent results on single CoQ 10 supplementation clinical trials in various metabolic disorders, the following meta-analysis tended to show more positive metabolic benefits in patients with advanced clinical stages, such as cardiovascular diseases, heart failure, or kidney failure, than the ones in early clinical phases, such as hypertension or dyslipidemia

Fleischer AB, Jr, Rosenthal DI , Bernard SA, O'Keefe EJ