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Notably, mitochondrial dysfunction induces endoplasmic reticulum (ER) stress, excessive reactive oxygen species (ROS) production, aberrant autophagy, apoptosis, and disrupted calcium ion homeostasis, culminating in inflammatory imbalance via activated signaling cascades [13,14,15,16,17]

c.e lipe syracuse Clifford Ehle (1887-1916) Willard Coughtry Lipe (1861-1924) -

Increased thermogenesis, mediated through the activation of brown adipose tissue, may contribute to fat mass loss and suppressed hunger hormone signaling

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