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Beyond presynaptic deficits, chronic dopamine depletion leads to postsynaptic adaptations, including downregulation of D2/3 receptors and inflammationmediated desensitization of downstream signaling pathways [201]

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Organ ECP 27 (6), 546552

doi: 10.3389/fphar.2024.1503064 85

One of its most important functions is neutralizing free radicals, which helps protect the body from oxidative damage

Whether these dynamic structural features could play a crucial role in modulating clathrin polymerization or a transition in the curvature of the lattice would need to be investigated