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ICARIA-MM was a randomized, multicenter, open-label study conducted in 24 countries across North America, Europe, and the AsiaPacific region [48]

It also attenuated lipopolysaccharide-induced acute lung injury in mice by inhibiting NF-B-mediated inflammatory responses 169

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Visual changes: subtle improvement in abdominal definition, slightly more visible obliques, mild reduction in lower abdominal "pouch." These changes are visible to the individual but unlikely to be noticed by others