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[DOI] [PMC free article] [PubMed] [Google Scholar] 363.Subramaniam, S

The gastrointestinal system has the largest immune population in the body and creates an interface between the external environment and the host and has been linked with numerous other autoimmune diseases [180] in addition to T1D

The receptor type I of TGF-1, also known as activin receptor-like kinase 5 (ALK5), phosphorylates Smad2 and 3 with its serine-threonine kinase activity

One such compound, 7, 27-dihydroxycholesterol, operates as an agonist for RORt, thus facilitating the differentiation of Th17 cells (66, 67)

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The fraction lost is 1 minus the fraction remaining just before the next dose
