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Several studies have demonstrated that NAD + metabolism is involved in neuronal function and in the pathophysiology of neurodegenerative diseases (Hikosaka et al., 2019) and that NAD + levels in tissues can produce beneficial therapeutical effects in this type of diseases (Kulikova et al., 2018)

One particularly intriguing and complex aspect of HIF-1 research is its interaction with ROS under normoxia

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