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Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice

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A third-generation physician who has also studied ayurvedic medicine, she calls B12 injections an integral part of her practice

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doi: 10.1186/s13045-018-0691-4 91 ChengQLiXLiuJYeQChenYTanSet al
