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RNA-seq analysis of hippocampal postmortem brain samples revealed a significant increase in MMP9 expression in male children with ASD compared to healthy controls [41]

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Impaired Absorption, Distribution, Metabolism, and Excretion of Nutrients and Other Substances Impaired digestion can lead to impaired ADME (absorption, distribution, metabolism, and excretion of nutrients), and acid reflux, as the digestive tract no longer becomes able to optimally carry out its functions

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doi: 10.1016/j.mayocp.2015.03.014