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Moreover, the data based on epidemiological analysis, clearly suggested that liver cirrhosis had inverse relationship with coffee consumption

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doi: 10.1136/annrheumdis-2012-202576 104 ShawkyAMAlmalkiFAAbdallaANAbdelazeemAHGoudaAM

Within HSCs, curcumin enhances PPAR functionality while mitigating oxidative stress through Ob-R dephosphorylation, subsequently suppressing Ob-R transcription and blocking leptin-mediated signaling, thereby abolishing leptins pro-activation effects on HSCs (Tang et al., 2009)

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PMID: 11205238 [Para 21 7] Bender AS, Reichelt W, Norenberg MD