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T cell survival in a quiescent state requires a sub-threshold signal provided by self-MHC/peptide recognition and some cell-activating factors

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Epstein-Barr virus (EBV) is a common virus that can cause infectious mononucleosis, also known as mono or the kissing disease. While many people recover fully from EBV, some continue to experience lingering symptoms, leading to chronic health issues

Furthermore, calcium indicators may be affected by pH fluctuations and struggle to differentiate between overlapping neuronal and astrocytic signals (225, 229)