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L-carnitine-supplementation in advanced pancreatic cancer (CARPAN)a randomized multicentre trial

10.4062/biomolther.2017.178 25 CiomborK.WhisenantJ.AyersG.EngC.GoffL.CardinD.et al (2023)

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While carnitine supplementation could have benefits, some recent studies suggest that chronic oral L-carnitine administration may be associated with an increased risk for atherosclerosis via increased trimethylamine (TMA) and/or trimethylamine N-Oxide (TMAO) levels (54, 55)

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Interestingly, this patient showed improvement in his fatigue